However, a Republican primary runoff looks probable.
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Hattie Caraway (D-AR) finished a distant fourth in Arkansas’s Democratic primary; then-Rep. William Fulbright went on to win the Democratic nomination in the runoff and the seat in November.
Plenty of Senate incumbents have lost renomination since then, but if there has been a runoff, the incumbent has at least made it to the second round.
Results During 26 years of follow-up encompassing 2 273 931 person years, 2431 women and 4098 men developed coronary heart disease.